Raymond P. Warrell, M.D. Selected Publications

1) Cvitkovic F, Armand JP, Tubiana-Hulin M, Rossi, Warrell RP: Randomized, double-blind, phase 2 trial of gallium nitrate compared with pamidronate for acute control of cancer-related hypercalcemia. Cancer J 12:47-53, 2006.

2) Soignet SL, Frankel SR, Douer D, Tallman MS, Kantarjian H, Calleja E, Stone RM, Kalaycio M, Scheinberg DA, Steinherz P, Sievers EL, Coutré S, Dahlberg S, Ellison R, Warrell RP: United States multicenter study of arsenic trioxide in patients with relapsed acute promyelocytic leukemia. Journal of Clinical Oncology 19:3852-60, 2001.

3) Rego EM, He L-Z, Warrell RP, Wang Z-G, Pandolfi PP: Retinoic acid and arsenic trioxide treatment in transgenic models of acute promyelocytic leukemia unravel the distinct natures of the leukemogenic process induced by the PML-RARα and PLZF-RARα oncoproteins. Proceedings of The National Academy of Sciences (USA) 97:10173-10180, 2000.

4) Soignet SL, Maslak P,Wang Z-G, Jhanwar S, Calleja E, Dardashti LJ, Corso D, DeBlasio A, Gabrilove J, Scheinberg DA, Pandolfi PP, Warrell RP: Complete remission after induction of non-terminal differentiation and apoptosis in acute promyelocytic leukemia by arsenic trioxide. New England Journal of Medicine 339:1341-1348, 1998.

5) Warrell RP, He L-Z, Richon V, Calleja E, Pandolfi PP: Targeted transcription therapy of acute promyelocytic leukemia using an inhibitor of histone deacetylase. Journal of the National Cancer Institute 90:1621-1625, 1998.

6) Warrell RP, de Thé H, Wang Z-Y, Degos L: Acute promyelocytic leukemia. New England Journal of Medicine 329:177-189, 1993.

7) Miller WH, Kakizuka A, Frankel SR, Warrell RP, Levine K, Evans R, Dmitrovsky E: Reverse transcriptase/polymerase chain reaction amplification for PML/RAR-α clarifies the diagnosis and detects minimal residual disease in acute promyelocytic leukemia. Proceedings of The National Academy of Sciences (USA) 89:2694-2698, 1992.

8) Warrell RP, Frankel SR, Miller WH, Scheinberg DA, Itri LM, Hittelman WN, Vyas R, Andreeff M, Tafuri A, Jakubowski A, Gabrilove J, Gordon M, Dmitrovsky E: Differentiation therapy of acute promyelocytic leukemia using tretinoin (all-trans retinoic acid). New England Journal of Medicine 324:1385-1393, 1991

9) Kakizuka A, Miller WH, Umesono K, Warrell RP, Frankel S, Murty VVS, Dmitrovsky E, Evans R: Chromosomal translocation t(15;17) in acute promyelocytic leukemia fuses the RAR-α receptor with a novel putative transcription factor PML. Cell 66:663-674, 1991.

10) Burtis WJ, Brady TG, Orloff JJ, Ersbak JB, Warrell RP, Wu TL, Mitnick ME, Broadus AE, Stewart AE: Immunochemical characterization of circulating parathyroid-like protein in patients with humoral hypercalcemia of cancer. New England Journal of Medicine 322:1106-1112, 1990.

11) Bockman RS, Repo MA, Warrell RP, Pounds JG, Schidlovsky G, Gordon BM, Jones KW: Distribution of trace levels of therapeutic gallium in bone as mapped by synchrotron x-ray microscopy. Proceedings of The National Academy of Sciences (USA) 87:4149-4153,1990.